Article

APPswe mutation causes functional deficits in endothelial cells generated by transient ETV2 overexpression in human iPSCs

2025-09-22

Abstract excerpt

<title>Abstract</title> <p>Background Brain endothelial cells (ECs) lining blood vessels are essential for the normal function of the brain. They form the first layer of the blood-brain barrier (BBB) and regulate nutrient exchange, immune responses, and angiogenesis. Numerous studies have reported the disruption of the BBB in neurodegenerative diseases, including Alzheimer’s disease (AD). However, the impact of c...

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Literature Corpus work: 9cc1ddf9-c369-57bc-abdc-07078f0c6498
DOI: 10.21203/rs.3.rs-6655027/v1

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