Article

Single Cell Epigenetics Reveal Cell-Cell Communication Networks in Normal and Abnormal Cardiac Morphogenesis

2022-07-25

Abstract excerpt

Communication between myriad cell types during organ formation underlies proper morphogenesis 1 . In cardiac development, reciprocal signaling between mesoderm progenitors and neural crest cells is essential, and its disruption leads to congenital heart malformations, the most common human birth defect. However, mechanistic interrogation of temporal gene networks and cis regulatory elements in this crosstalk is...

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Literature Corpus work: 9bceb098-e8fa-544d-b8ae-3f5dd8a8f4ed
DOI: 10.1101/2022.07.25.501458

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