Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation

17 Aug 2020

Abstract excerpt

Perturbation of addition of second heart field (SHF) cardiac progenitor cells to the poles of the heart tube results in congenital heart defects (CHD). The transcriptional programs and upstream regulatory events operating in different subpopulations of the SHF remain unclear. Here, we profile the transcriptome and chromatin accessibility of anterior and posterior SHF sub-populations at genome-wide levels and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Congenital Heart Disease Studies

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32804075
DOI: 10.7554/elife.55124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiationPMID 32804075Read ↗

Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development.Semantic proximity Read ↗

Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.Semantic proximity Read ↗

A molecular and genetic outline of cardiac morphogenesisSemantic proximity Read ↗

Genetic and Epigenetic Control of Heart Development.Semantic proximity Read ↗

Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo.Semantic proximity Read ↗

T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart fieldSemantic proximity Read ↗

Isl2b regulates anterior second heart field development in zebrafishSemantic proximity Read ↗

Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineagesSemantic proximity Read ↗

BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heartSemantic proximity Read ↗

A Decade of Advances in the Molecular Embryology and Genetics Underlying Congenital Heart DefectsSemantic proximity Read ↗

Chromatin remodeler Brahma safeguards canalization in cardiac mesoderm differentiationSemantic proximity Read ↗

Single Cell Epigenetics Reveal Cell-Cell Communication Networks in Normal and Abnormal Cardiac MorphogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.