Article

Dynamics of Cardiomyocyte Transcriptome and Chromatin Landscape Demarcates Key Events of Heart Development

2018-12-07

Abstract excerpt

<h4>ABSTRACT</h4> The development of an organ involves dynamic regulation of gene transcription and complex multipathway interactions. To better understand transcriptional regulatory mechanism driving heart development and the consequences of its disruption, we isolated cardiomyocytes (CMs) from wild-type zebrafish embryos at 24, 48 and 72 hours post fertilization corresponding to heart looping, chamber formation...

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Literature Corpus work: 2cc4bc60-bb9e-578d-b158-f8ce9e3f1517
DOI: 10.1101/488593

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