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Patient-centered Transcriptomic and Multimodal Neuroimaging Determinants of Clinical Progression, Physical Activity and Treatment Needs in Parkinson’s Disease

2024-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease is a complex and multifactorial disorder, but how its biological and clinical complexity emerge from molecular to macroscopic brain interactions remains poorly understood. Here, we use a personalized multiscale generative brain model to characterize direct spatiotemporal links between genes and multimodal neuroimaging-derived biological factors in PD. We identified a set of ge...

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Literature Corpus work
9a62dd50-ab58-56db-96c8-0779ec7780a6
DOI
10.1101/2024.09.25.24314374
Open publication

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Patient-centered Transcriptomic and Multimodal Neuroimaging Determinants of Clinical Progression, Physical Activity and Treatment Needs in Parkinson’s DiseaseDOI 10.1101/2024.09.25.24314374
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