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Identification of Parkinson’s disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data

9 Jul 2024

Abstract excerpt

Parkinson's disease (PD) is a serious neurodegenerative disorder marked by significant clinical and progression heterogeneity. This study aimed at addressing heterogeneity of PD through integrative analysis of various data modalities. We analyzed clinical progression data (≥5 years) of individuals with de novo PD using machine learning and deep learning, to characterize individuals' phenotypic progression...

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PMID: 38982243
DOI: 10.1038/s41746-024-01175-9

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