Article

Identification of Parkinson PACE subtypes and repurposing treatments through integrative analyses of multimodal clinical progression, neuroimaging, genetic, and transcriptomic data

2021-07-22

Abstract excerpt

Parkinson’s disease (PD) is a progressive neurodegenerative disorder marked by significant clinical and progression heterogeneity resulting from complex pathophysiological mechanisms. This study aimed at addressing heterogeneity of PD through the integrative analysis of a broad spectrum of data sources. We analyzed clinical progression data spanning over 5 years from individuals with de novo PD, using machine lear...

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Literature Corpus work: b15cceac-38a8-52a4-ba5f-adae4ef62c44
DOI: 10.1101/2021.07.18.21260731

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