Article

Identifying the genetic links between Parkinson’s disease and non-motor symptoms: novel insights into disease mechanisms

2023-09-13

Abstract excerpt

<title>Abstract</title> <p>Understanding the biological mechanisms that underlie the non-motor symptoms of Parkinson’s disease (PD) requires comprehensive frameworks that unravel the complex interplay of genetic risk factors. Here, we used a disease-agnostic brain cortex gene regulatory network integrated with Mendelian Randomization analyses to identify 19 genes whose changes in expression are causal for PD. We...

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Literature Corpus work: c4eef7da-be5a-5fb6-af5a-766f1d9f902b
DOI: 10.21203/rs.3.rs-3177049/v1

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