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Article

Integrative genomic analysis of Neurogenin2 reprogramming of human iPSCs

2020-01-01

Abstract excerpt

Direct cell reprogramming is a rapidly growing field that has challenged traditional concepts of cellular identity. The expression of Neurogenin 2 (NGN2) results in rapid reprogramming of human pluripotent stem cells (PSCs) into functional excitatory neurons. My lab has previously demonstrated that gene targeting the components of a Tet-On system overexpressing NGN2 into two separate safe harbour sites overcome ge...

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Literature Corpus work
9a22d91b-5e55-57b3-8f0c-d6dbfa1ebb1e
DOI
10.17863/cam.64828
Open publication

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Integrative genomic analysis of Neurogenin2 reprogramming of human iPSCsDOI 10.17863/cam.64828
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