Article
miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro.
Cells - 25 Feb 2020
Ishikawa Mitsuru, Aoyama Takeshi, Shibata Shoichiro, Sone Takefumi, Miyoshi Hiroyuki, Watanabe Hirotaka, Nakamura Mari, Morota Saori, Uchino Hiroyuki, Yoo Andrew S, Okano Hideyuki
Abstract excerpt
Obtaining differentiated cells with high physiological functions by an efficient, but simple and rapid differentiation method is crucial for modeling neuronal diseases in vitro using human pluripotent stem cells (hPSCs). Currently, methods involving the transient expression of one or a couple of transcription factors have been established as techniques for inducing neuronal differentiation in a rapid, single...
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