Article

<i>NEUROG2</i> regulates a human-specific neurodevelopmental gene regulatory program

2024-01-11

Abstract excerpt

<h4>ABSTRACT</h4> Unique hallmarks of human neocortical development include slower rates of neurogenesis and the establishment of an extracellular matrix-rich, outer-subventricular zone that supports basal neural progenitor cell expansion. How gene regulatory networks have evolved to support these human-specific neurodevelopmental features is poorly understood. Mining single cell data from cerebral organoids and...

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Literature Corpus work: cfd509c6-bd42-50ee-a6fa-d832bcdb51ce
DOI: 10.1101/2024.01.11.575174

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