Article

Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells

2022-09-07

Abstract excerpt

<h4>ABSTRACT</h4> Astrocytes play essential roles in normal brain function, with dysfunction implicated in diverse developmental and degenerative disease processes. Emerging evidence of profound species divergent features of astrocytes coupled with the relative inaccessibility of human brain tissue underscore the utility of human pluripotent stem cell (hPSC) technologies for the generation and study of human astr...

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Literature Corpus work: 9b4f6439-006f-57e5-b09d-8af81af8e386
DOI: 10.1101/2022.09.07.507028

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