Article

Human cortical neurons rapidly generated by direct ES cell programming integrate into stroke-injured rat cortex

2024-03-17

Abstract excerpt

<h4>ABSTRACT</h4> Stroke is a major cause of long-term disability in adult humans, the neuronal loss leading to motor, sensory, and cognitive impairments. Replacement of dead neurons by intracerebral transplantation of stem cell-derived neurons for reconstruction of injured neuronal networks has potential to become a novel therapeutic strategy to promote functional recovery after stroke. Here we describe a rapid...

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Literature Corpus work: ad92cd5c-ff02-59cd-8406-605cebb57d62
DOI: 10.1101/2024.03.15.585240

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