Article

Genetic and environmental imprints on T cell receptor repertoires as predictors of graft-versus-host disease

2025-12-25

Abstract excerpt

<h4> Abstract </h4> Hematopoietic cell transplantation (HCT) as potentially curative treatment for patients with hematologic malignancies relies on T cells to mediate the potentially curative graft-versus-tumor (GVT) effect, which may be associated with graft-versus-host disease (GVHD), a potentially life-threatening complication. T cells recognize peptides presented by Human Leukocyte Antigen (HLA) molecules. I...

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Literature Corpus work: 99cd788d-886e-5f3f-b5b1-99b66b37e548
DOI: 10.64898/2025.12.23.696252

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