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Article

Potential of TCR sequencing in graft-versus-host disease

7 Dec 2022

Abstract excerpt

Graft-versus-host disease (GvHD) remains one of the major complications following allogeneic haematopoietic stem cell transplantation (allo-HSCT). GvHD can occur in almost every tissue, with the skin, liver, and intestines being the mainly affected organs. T cells are implicated in initiating GvHD. T cells identify a broad range of antigens and mediate the immune response through receptors on their surfaces (T...

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PMID: 36477111
DOI: 10.1038/s41409-022-01885-2

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