Article

Cryptic adaptor protein interactions regulate DNA replication initiation

2018-05-04

Abstract excerpt

DNA replication is a fundamental biological process that is tightly regulated in all living cells. In bacteria, the master regulator DnaA controls when and where replication begins by building a step-wise complex that loads the replicative helicase onto chromosomal DNA. In many bacteria, DnaA requires the adaptor proteins DnaD and DnaB to aid DnaA during helicase loading. How DnaA, its adaptors, and the helicase f...

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Literature Corpus work: 95699200-d6c2-5959-98dc-742eba214da5
DOI: 10.1101/313882

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