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Article

Origin activation requires both replicative and accessory helicases during T4 infection.

Journal of molecular biology - 11 Apr 2008

Brister J Rodney

Abstract excerpt

The bacteriophage T4 has served as an in vitro model for the study of DNA replication for several decades, yet less is known about this process during infection. Recent work has shown that viral DNA synthesis is initiated from at least five origins of replication distributed across the 172 kb chromosome, but continued synthesis is dependent on recombination. Two proteins are predicted to facilitate loading of the...

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Share to Bacteriophage T4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18314134
DOI: 10.1016/j.jmb.2008.02.002
PMCID: PMC2374744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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