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Article

HdaB: a novel and conserved DnaA-related protein that targets the RIDA process to stimulate replication initiation.

Nucleic acids research - 18 Mar 2020

Frandi Antonio, Collier Justine

Abstract excerpt

Exquisite control of the DnaA initiator is critical to ensure that bacteria initiate chromosome replication in a cell cycle-coordinated manner. In many bacteria, the DnaA-related and replisome-associated Hda/HdaA protein interacts with DnaA to trigger the Regulatory Inactivation of DnaA (RIDA) and prevent over-initiation events. In the Caulobacter crescentus Alphaproteobacterium, the RIDA process also targets...

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Identifiers

PMID: 31875223
DOI: 10.1093/nar/gkz1193
PMCID: PMC7049699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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