Article

β-carotene accelerates the resolution of atherosclerosis in mice

2023-03-10

Abstract excerpt

<h4>ABSTRACT</h4> β-carotene oxygenase 1 (BCO1) catalyzes the cleavage of β-carotene to form vitamin A. Besides its role in vision, vitamin A regulates the expression of genes involved in lipid metabolism and immune cell differentiation. BCO1 activity is associated with the reduction of plasma cholesterol in humans and mice, while dietary β-carotene reduces hepatic lipid secretion and delays atherosclerosis progr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93a63409-6924-5be7-8706-9ff514b4d893
DOI: 10.1101/2023.03.07.531563

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

β-carotene accelerates the resolution of atherosclerosis in miceDOI 10.1101/2023.03.07.531563Read

UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses.Semantic proximity Read

Ablation of carotenoid cleavage enzymes (BCO1 and BCO2) induced hepatic steatosis by altering the farnesoid X receptor/miR-34a/sirtuin 1 pathway.Semantic proximity Read

Weak UVB Irradiation Promotes Macrophage M2 Polarization and Stabilizes Atherosclerosis.Semantic proximity Read

Targeting B cells in atherosclerosis: closing the gap from bench to bedside.Semantic proximity Read

Inhibition of glycosphingolipid synthesis reverses skin inflammation and hair loss in ApoE-/- mice fed western diet.Semantic proximity Read

In Vitro Differentiation of Naïve CD4⁺ T Cells: A Tool for Understanding the Development of Atherosclerosis.Semantic proximity Read

CD8(+)CD25(+) T cells reduce atherosclerosis in apoE(-/-) mice.Semantic proximity Read

Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice.Semantic proximity Read

Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid researchSemantic proximity Read

Orally administered eicosapentaenoic acid induces rapid regression of atherosclerosis via modulating the phenotype of dendritic cells in LDL receptor-deficient mice.Semantic proximity Read

Marginal Zone B cells produce 'natural' atheroprotective IgM antibodies in a T-cell-dependent mannerSemantic proximity Read

Comparative Effects of Diet-Induced Lipid Lowering Versus Lipid Lowering Along With Apo A-I Milano Gene Therapy on Regression of Atherosclerosis.Semantic proximity Read