Article

Marginal Zone B cells produce 'natural' atheroprotective IgM antibodies in a T-cell-dependent manner

2022-06-17

Abstract excerpt

<title>Abstract</title> <p>The adaptive immune response plays an important role in atherosclerosis. In response to a high fat/high cholesterol diet, marginal zone B (MZB) cells activate an atheroprotective programme by regulating the differentiation and accumulation of T follicular helper (Tfh) cells. On the other hand, Tfh cells activate the germinal centre response, which promotes atherosclerosis in part throug...

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Literature Corpus work: 5a618945-e20b-5f4e-842b-6da2a6a14164
DOI: 10.21203/rs.3.rs-1753743/v1

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