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Article

Targeting B cells in atherosclerosis: closing the gap from bench to bedside.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2015

Tsiantoulas Dimitrios, Sage Andrew P, Mallat Ziad, Binder Christoph J

Abstract excerpt

Atherosclerotic plaque formation is strongly influenced by different arms of the immune system, including B lymphocytes. B cells are divided into 2 main families: the B1 and the B2 cells. B1 cells are atheroprotective mainly via the production of natural IgM antibodies that bind oxidized low-density lipoprotein and apoptotic cells. B2 cells, which include follicular and marginal zone B cells, are suggested to be...

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Identifiers

PMID: 25359862
DOI: 10.1161/ATVBAHA.114.303569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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