Article
In Vitro Differentiation of Naïve CD4⁺ T Cells: A Tool for Understanding the Development of Atherosclerosis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Iborra Salvador, González-Granado Jose M
Abstract excerpt
A complete knowledge of atherosclerosis requires a better understanding of how innate and adaptive immunity operate systemically and locally within the arterial wall. T-helper 1 (Th1) lymphocyte responses have proatherogenic effects in mice, contrasting with the responses of T regulatory cells (Tregs), which can suppress growth of atherosclerotic lesions. An imbalance in the differentiation of T-helper cells may...
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