Article

Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood

2021-05-26

Abstract excerpt

<title>Abstract</title> <p>Large scale genetic association studies have identified many trait-associated variants and understanding the role of these variants in downstream regulation of gene-expressions can uncover important mediating biological mechanisms. In this study, we propose Aggregative <italic>tRans</italic> assoCiation to detect pHenotype specIfic gEne-sets (ARCHIE), as a method to establish links betw...

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Literature Corpus work: 93126cbb-6ffc-5e8d-92d6-2f427ce4059b
DOI: 10.21203/rs.3.rs-523532/v1

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