Article

Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

2018-10-19

Abstract excerpt

<h4>Summary</h4> While many disease-associated variants have been identified through genome-wide association studies, their downstream molecular consequences remain unclear. To identify these effects, we performed cis- and trans-expression quantitative trait locus (eQTL) analysis in blood from 31,684 individuals through the eQTLGen Consortium. We observed that cis -eQTLs can be detected for 88% of the studied...

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Literature Corpus work: 1e999d22-2065-5fd2-8b43-14b4315912e2
DOI: 10.1101/447367

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