Article

Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood

2020-09-30

Abstract excerpt

Large scale genetic association studies have identified many trait-associated variants and understanding the role of these variants in downstream regulation of gene-expressions can uncover important mediating biological mechanisms. In this study, we propose Aggregative tRans assoCiation to detect pHenotype specIfic gEne-sets (ARCHIE), as a method to establish links between sets of known genetic variants associated...

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Literature Corpus work: 9c32acdf-7e0c-505b-b0db-f387990f28f9
DOI: 10.1101/2020.09.29.20204388

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