Article

Imputed gene associations identify replicable <i>trans</i> -acting genes enriched in transcription pathways and complex traits

2018-11-19

Abstract excerpt

Regulation of gene expression is an important mechanism through which genetic variation can affect complex traits. A substantial portion of gene expression variation can be explained by both local ( cis ) and distal ( trans ) genetic variation. Much progress has been made in uncovering cis -acting expression quantitative trait loci (cis-eQTL), but trans -eQTL have been more difficult to identify and replicate....

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Literature Corpus work: 5d3176f6-da04-5dc2-9e57-26b2250776b1
DOI: 10.1101/471748

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