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Article

Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.

Human molecular genetics - 15 Aug 2015

Kirsten Holger, Al-Hasani Hoor, Holdt Lesca, Gross Arnd, Beutner Frank, Krohn Knut, Horn Katrin, Ahnert Peter, Burkhardt Ralph, Reiche Kristin, Hackermüller Jörg, Löffler Markus, Teupser Daniel, Thiery Joachim, Scholz Markus

Abstract excerpt

Genetics of gene expression (eQTLs or expression QTLs) has proved an indispensable tool for understanding biological pathways and pathomechanisms of trait-associated SNPs. However, power of most genome-wide eQTL studies is still limited. We performed a large eQTL study in peripheral blood mononuc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Polymorphism, Single Nucleotide

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Share to Regulatory Sequences, Nucleic Acid

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Identifiers

PMID: 26019233
DOI: 10.1093/hmg/ddv194
PMCID: PMC4512630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26019233-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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