Article

Functional characterisation of A2A receptor thermostable mutants using a yeast signalling assay

2014-01-01

Abstract excerpt

G-protein-coupled receptors (GPCR) are transmembrane proteins that play a crucial role in the communication of cells with their external environment. In the last few years, several GPCR crystal structures have been solved using genetically engineered protein. The turkey β1-adrenergic receptor, the human neutrotensin 1 receptor and the adenosine A2A receptor (A2AR) structures involved the introduction of stabilizin...

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Literature Corpus work: 91d28fdb-e072-58b7-9c4f-d455cd4350cf
DOI: 10.25560/24701

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