Article

Integrated cross-study datasets of genetic dependencies in cancer

2020-05-23

Abstract excerpt

CRISPR-Cas9 viability screens are increasingly performed at a genome-wide scale across large panels of cell lines to identify new therapeutic targets for precision cancer therapy. Integrating the datasets resulting from these studies is necessary to adequately represent the heterogeneity of human cancers and to assemble a comprehensive map of cancer genetic vulnerabilities. Here, we integrated the two largest publ...

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Literature Corpus work: 8fb5f0b6-a85a-53b9-b9f2-aacac12e30b6
DOI: 10.1101/2020.05.22.110247

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