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Article

Characterizing genes associated with cancer using the CRISPR/Cas9 system: A systematic review of genes and methodological approaches.

Gene - 30 Jul 2022

Gonzalez-Salinas Fernando, Martinez-Amador Claudia, Trevino Victor

Abstract excerpt

The CRISPR/Cas9 system enables a versatile set of genomes editing and genetic-based disease modeling tools due to its high specificity, efficiency, and accessible design and implementation. In cancer, the CRISPR/Cas9 system has been used to characterize genes and explore different mechanisms implicated in tumorigenesis. Different experimental strategies have been proposed in recent years, showing dependency on...

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PMID: 35598687
DOI: 10.1016/j.gene.2022.146595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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