Article
CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer.
Cell systems - 26 Jul 2017
Bridgett Stephen, Campbell James, Lord Christopher J, Ryan Colm J
Abstract excerpt
Genes whose function is selectively essential in the presence of cancer-associated genetic aberrations represent promising targets for the development of precision therapeutics. Here, we present CancerGD, a resource that integrates genotypic profiling with large-scale loss-of-function genetic screens in tumor cell lines to identify such genetic dependencies. CancerGD provides tools for searching, visualizing, and...
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