Article

Contribution of 3D genome topological domains to genetic risk of cancers: a genome-wide computational study

2021-08-19

Abstract excerpt

<title>Abstract</title> <p>Background Genome-wide association studies have identified statistical associations between various diseases, including cancers, and a large number of single-nucleotide polymorphisms (SNPs). However, they provide no direct explanation of the mechanisms underlying the association. Based on the recent discovery that changes in 3-dimensional genome organization may have functional consequ...

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Literature Corpus work: 8ce99e95-51cf-55af-9341-43c7d4ed94e9
DOI: 10.21203/rs.3.rs-800781/v1

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