Article

Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure

2020-10-07

Abstract excerpt

Numerous genome-wide association studies (GWAS) conducted to date revealed genetic variants associated with various diseases, including breast and prostate cancers. Despite the availability of these large-scale data, relatively few variants have been functionally characterized, mainly because the majority of single-nucleotide polymorphisms (SNPs) map to the non-coding regions of the human genome. The functional ch...

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Literature Corpus work: 2827d856-c6bc-5295-af5b-f0c9f4754109
DOI: 10.1101/2020.10.06.328567

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