Article

Genes and Pathways Comprising the Human and Mouse ORFeomes Display Distinct Codon Bias Signatures that Can Regulate Protein Levels

2025-02-04

Abstract excerpt

Arginine, glutamic acid and selenocysteine based codon bias has been shown to regulate the translation of specific mRNAs for proteins that participate in stress responses, cell cycle and transcriptional regulation. Defining codon-bias in gene networks has the potential to identify other pathways under translational control. Here we have used computational methods to analyze the ORFeome of all unique human (19,711)...

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Literature Corpus work: 8c82551f-7262-529c-9050-39c34fc24dee
DOI: 10.1101/2025.02.03.636209

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Genes and Pathways Comprising the Human and Mouse ORFeomes Display Distinct Codon Bias Signatures that Can Regulate Protein LevelsDOI 10.1101/2025.02.03.636209Read

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