Article

Multi-level Analysis of Codon Usage Patterns Reveals Systematic Optimization of Oncogenic Gene Expression in Pancreatic Cancer

2026-04-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Codon usage bias, the non-random usage of synonymous codons in coding sequences, represents a fundamental feature of genomic organization that has been largely understudied in cancer biology. Pancreatic ductal adenocarcinoma (PDAC), the predominant subtype of pancreatic cancer, is characterized by aggressive disease progression and limited therapeutic options, necessitating...

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Literature Corpus work: 7e0e7faa-1948-5976-9da1-12e712e61543
DOI: 10.64898/2026.04.24.720399

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