Article

Codon Bias Confers Stability to mRNAs via ILF2 in Humans

2019-03-24

Abstract excerpt

Codon bias has been implicated as one of the major factors contributing to mRNA stability in yeast. However, the effects of codon-bias on mRNA stability remain unclear in humans. Here we show that human cells possess a mechanism to modulate RNA stability through a unique codon bias different from that of yeast. Bioinformatics analysis showed that codons could be clustered into two distinct groups – codons with G o...

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Literature Corpus work: 302a1184-8810-5f94-9caf-96270cb57fb3
DOI: 10.1101/585992

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