Article

Transcriptomic, proteomic and functional consequences of codon usage bias in human cells during heterologous gene expression

2022-01-10

Abstract excerpt

<h4>ABSTRACT</h4> Differences in codon frequency between genomes, genes, or positions along a gene, modulate transcription and translation efficiency, leading to phenotypic and functional differences. Here, we present a multiscale analysis of the effects of synonymous codon recoding during heterologous gene expression in human cells, quantifying the phenotypic consequences of codon usage bias at different molecul...

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Literature Corpus work: d4fc0d1b-f5cc-5804-8f20-c914c197e08e
DOI: 10.1101/2022.01.07.475042

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