Article

Distinct responses to rare codons in select <i>Drosophila</i> tissues

2022-01-06

Abstract excerpt

<h4>ABSTRACT</h4> Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression. Here, we use codon-modified reporters to perform an organism-wide screen in Drosophila melanogaster for distinct tissue responses to codon usage bias. These reporters reveal a cliff-like decline of protei...

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Literature Corpus work: efb17499-51fd-5d57-8e2c-f19f6ddd4424
DOI: 10.1101/2022.01.06.475284

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