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Vascularized Brain Assembloids with Enhanced Cellular Complexity Provide Insights into The Cellular Deficits of Tauopathy

2023-07-02

Abstract excerpt

Advanced technologies have enabled the engineering of self-organized 3-dimensional (3D) cellular structures from human induced pluripotent stem cells (hiPSCs), namely organoids, which recapitulate some key features of tissue development and functions of the human central nervous system (CNS). While hiPSC-derived 3D CNS organoids hold promise in providing a human-specific platform for studying CNS development and d...

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Literature Corpus work
aba8416e-47a5-5038-a7ce-3e388fe465c6
DOI
10.1101/2023.06.30.547293
Open publication

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Vascularized Brain Assembloids with Enhanced Cellular Complexity Provide Insights into The Cellular Deficits of TauopathyDOI 10.1101/2023.06.30.547293
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