Article

Neurophysiological alterations in the nucleus reuniens of a mouse model of Alzheimer’s disease

2019-05-20

Abstract excerpt

Transgenic mice that overproduce beta-amyloid (Aβ) peptides exhibit neurophysiological alterations at the cellular, synaptic and network levels. Recently, increased neuronal activity in nucleus reuniens (Re), has been linked to hyperexcitability within hippocampal-thalamo-cortical networks in the J20 mouse model of amyloidopathy. Here in vitro whole-cell patch clamp recordings were used to compare old pathology-b...

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Literature Corpus work: 8a4e03df-67ac-5342-8b70-f6a726e5a913
DOI: 10.1101/643023

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