Article

Single cell functional genomics reveals the importance of mitochondria in cell-to-cell variation in proliferation, drug resistance and mutation outcome

2018-06-13

Abstract excerpt

Mutations frequently have outcomes that differ across individuals, even when these individuals are genetically identical and share a common environment. Moreover, individual microbial and mammalian cells can vary substantially in their proliferation rates, stress tolerance, and drug resistance, with important implications for the treatment of infections and cancer. To investigate the causes of cell-to-cell variati...

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Literature Corpus work: 89186574-c7fe-5246-bb5a-04ca4dde94c6
DOI: 10.1101/346361

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