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Article

System-level impact of mitochondria on fungal virulence: to metabolism and beyond

22 May 2015

Abstract excerpt

The mitochondrion plays wide-ranging roles in eukaryotic cell physiology. In pathogenic fungi, this central metabolic organelle mediates a range of functions related to disease, from fitness of the pathogen to developmental and morphogenetic transitions to antifungal drug susceptibility. In this review, we present the latest findings in this area. We focus on likely mechanisms of mitochondrial impact on fungal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26002841
DOI: 10.1093/femsyr/fov027

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