Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial genetics through the lens of single-cell multi-omics.

Nature genetics - 1 Jul 2024

Nitsch Lena, Lareau Caleb A, Ludwig Leif S

Abstract excerpt

Mitochondria carry their own genetic information encoding for a subset of protein-coding genes and translational machinery essential for cellular respiration and metabolism. Despite its small size, the mitochondrial genome, its natural genetic variation and molecular phenotypes have been challenging to study using bulk sequencing approaches, due to its variation in cellular copy number, non-Mendelian modes of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to DNA, Mitochondrial
Share to Genome, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Mitochondria

Share to Multiomics

Share to Mutation

Share to Single-Cell Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 38951641
DOI: 10.1038/s41588-024-01794-8
PMCID: PMC11260401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial genetics through the lens of single-cell multi-omics.PMID 38951641Read ↗

Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility.Semantic proximity Read ↗

Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.Semantic proximity Read ↗

Sequencing and characterizing human mitochondrial genomes in the biobank-based genomic research paradigm.Semantic proximity Read ↗

Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.Semantic proximity Read ↗

Single-cell multi-omics resolved analysis of mitochondrial genome-wide mutational burden, constraint, and mosaicismSemantic proximity Read ↗

Mitochondrial DNA: Inherent Complexities Relevant to Genetic Analyses.Semantic proximity Read ↗

Detection methods for mitochondrial DNA heteroplasmy and their potential single-cell applications in cancer.Semantic proximity Read ↗

Mitochondrial Diseases: A Diagnostic Revolution.Semantic proximity Read ↗

Single-cell Individual Complete mtDNA Sequencing Uncovers Hidden Mitochondrial Heterogeneity in Human and Mouse OocytesSemantic proximity Read ↗

Long-read MitoScope reveals tissue-resolved somatic mitochondrial variation and landscape of nuclear-embedded mitochondrial sequencesSemantic proximity Read ↗

Exploring Heteroplasmic Variants in mtDNA: Insights from Single-Cell TranscriptomicsSemantic proximity Read ↗

Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.