Article
Microbial cell individuality and the underlying sources of heterogeneity.
Nature reviews. Microbiology - 1 Aug 2006
Avery Simon V
Abstract excerpt
Single cells in genetically homogeneous microbial cultures exhibit marked phenotypic individuality, a biological phenomenon that is considered to bolster the fitness of populations. Major phenotypes that are characterized by heterogeneity span the breadth of microbiology, in fields ranging from pathogenicity to ecology. The cell cycle, cell ageing and epigenetic regulation are proven drivers of heterogeneity in...
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