Article

Lysosomes cell autonomously regulate myeloid cell states and immune responses

2024-11-13

Abstract excerpt

<h4>ABSTRACT</h4> Myeloid cells maintain tissue homeostasis via the recognition, engulfment, and lysosomal clearance of dying cells and cellular debris, which is often accompanied by changes from homeostatic to reactive states. While a role for phagocytic receptors in gating these transitions has been described 1,2 , less is known about if and how lysosomes can contribute to transcriptional and functional plasti...

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Literature Corpus work: bd18fa0a-50ef-5ce5-9043-66c184358d3f
DOI: 10.1101/2024.11.11.623074

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