Article

Diesel exhaust particles disrupt mouse and human iPSC-derived microglial function and Amyloid-β clearance in Alzheimer’s disease models

2026-07-23

Abstract excerpt

Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders, yet the environmental drivers that accelerate its progression remain poorly defined. Traffic-related air pollution is emerging as a modifiable AD risk factor, but how inhaled particles perturb microglial clearance of amyloid beta (Aβ) is unknown. Microglia are the principal Aβ-clearing phagocytes of the brain. Here, we showed that expo...

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Literature Corpus work: ba51dbbb-6d0c-500d-8231-b6b8aa049afa
DOI: 10.64898/2026.07.20.739493

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