Article

CHIC2 and STUB1 regulate interferon-γ receptor cell surface expression

2020-01-01

Abstract excerpt

The regulated expression of cell surface receptors is essential for cellular homeostasis and defective in disease states. Receptor regulation is particularly important as receptor internalization limits the duration and intensity of substrate signaling. Interferon-γ (IFN-γ), a critical antiviral cytokine, transduces its signal through the interferon-γ receptor (IFNGR), a single-pass heterodimeric receptor composed...

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Literature Corpus work: 87aa9dd6-640b-50a5-b558-7f9e16346e19
DOI: 10.17863/cam.45868

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