Article

Identification of novel regulators of lymphocyte development and differentiation using CRISPR-Cas9 screens

2020-01-01

Abstract excerpt

T helper-2 (TH2) and type 2 innate lymphoid cells (ILC2s) play important roles in parasite expulsion, wound healing and allergic diseases through the expression of type 2 cytokines including IL-4, IL-5 and IL-13. Central to lymphocyte function are molecules required for differentiation and development. Several lineage-specifying transcription factors and other signalling molecules are known to be important for TH2...

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Literature Corpus work: dd8bb38d-0fe3-5816-839d-0b0586b1c91b
DOI: 10.17863/cam.59138

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