Article

Genome-wide Identification of Immune Regulatory Networks: Comparative Performance of RNAi and CRISPRi in Host Factor Discovery

2026-01-14

Abstract excerpt

<title>Abstract</title> <p>Viruses systematically exploit numerous host immune regulatory factors to establish infections, yet endogenous suppression mechanisms remain inadequately characterized. This review examines RNA interference (RNAi) and CRISPR interference (CRISPRi) screening methodologies for systematically identifying host factors that negatively regulate immune signaling pathways, addressing fundamenta...

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Literature Corpus work: a6286ea9-cbeb-5295-824b-079fc49e8c81
DOI: 10.21203/rs.3.rs-7688073/v1

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