Article

Regulation of Macrophage IFNγ-Stimulated Gene Expression by the Transcriptional Coregulator CITED1

2022-08-16

Abstract excerpt

Macrophages are highly dynamic innate immune cells that adopt temporary phenotypes, known as polarization states, in response to changing environmental signals to combat microbial infection and contribute to the maintenance of tissue homeostasis. During the early stages of an infection, exposure to interferon-gamma (IFNγ) and microbial ligands induce M1 polarization, a heightened proinflammatory anti-microbial sta...

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Literature Corpus work: b9f64998-36a6-5afd-b1ac-9837eb6c38d7
DOI: 10.1101/2022.08.16.504142

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